Is There Really Any Difference? What’s the difference between B2B and B2C marketing? Is there any difference at all? While both B2B and B2C marketers may use the same terminologies, the methods and tactics they use can vary greatly given their different needs. For those who are new to marketing or are exploring the “other side” of the marketing world, read on to learn more about the similarities and differences between B2B and B2C marketing.